Author

M.Z. Malecka

Max Delbrück Center

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Neuroscience· 1

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Dominik SeelowiD· 1 shared Freyda Lenihan-GeelsiD· 1 shared Heiko KrudeiD· 1 shared Markus SchuelkeiD· 1 shared Martin BommeriD· 1 shared Robert OpitziD· 1 shared Sebastian ProftiD· 1 shared Udo HeinemanniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Dominik SeelowORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintMar 2, 2026

Quantification of the effects of single nucleotide variants in NKX2.1 transcription factor binding sites

Freyda Lenihan-Geels, Sebastian Proft, Martin Bommer…·M.Z. Malecka

The paper quantifies how single nucleotide variants affect NKX2.1 transcription factor binding and uses neural networks to predict disease-causing variants in regulatory regions.

DOI 10.64898/2026.02.27.708450

humanChIP-seq

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