Author

Heiko Krude

Humboldt-Universität zu BerlinORCID 0000-0002-1169-0348Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Markus SchuelkeiD· 2 shared Robert OpitziD· 2 shared Dominik SeelowiD· 1 shared Eugenio GraceffoiD· 1 shared Freyda Lenihan-GeelsiD· 1 shared M.Z. Malecka· 1 shared Martin BommeriD· 1 shared Matthias MeggesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Markus SchuelkeORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 2, 2026

Quantification of the effects of single nucleotide variants in NKX2.1 transcription factor binding sites

Freyda Lenihan-Geels, Sebastian Proft, Martin Bommer…·M.Z. Malecka

The paper quantifies how single nucleotide variants affect NKX2.1 transcription factor binding and uses neural networks to predict disease-causing variants in regulatory regions.

DOI 10.64898/2026.02.27.708450

humanChIP-seq

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GeneticsbioRxivPreprintDec 22, 2023

RNA-sequencing reveals strong predominance of THRA splicing isoform 2 in the developing and adult human brain

Eugenio Graceffo, Robert Opitz, Matthias Megges…·Markus Schuelke

The paper uses RNA-sequencing to show that THRA2 is predominantly expressed in human brain development and adult central nervous system tissues.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky