Lipid nanoemulsion incorporating DOTAP reverse micelles as clinically translatable carriers of ALDH inhibitors for lung cancer therapy
Maria Irujo, Laura Poussereau, Maïssam Ezziani, Clotilde Joubert, Chloé Prunier, Julien Vollaire, Véronique Josserand, Cédric Sarazin, Axel Kattar, Daphna Fenel, Eleftherios Zarkadas, Alice Gaudin, Mileidys Alea Perez, Isabelle Texier
This paper develops a lipid nanoemulsion with DOTAP reverse micelles to deliver ALDH1A3 inhibitors for lung cancer treatment, showing high efficacy and structural stability.
bioRxiv · Jun 16, 2025 · PreprintBioengineering