Increased numbers of CD4+ T-cells in hypocretin/orexin region of Narcolepsy Type 1
Ling Shan, Milo Fonville, Mabel Hoekstra, Rolf Fronczek, Joost Smolders, Dick Frans Swaab
The paper identifies an 11-fold increase in CD4+ T-cells in the hypocretin region of NT1 brains, correlating with symptom severity.
Annals of Neurology · Mar 14, 2026Peer-reviewedNeuroscience