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Macie S. Sheridan

Johns Hopkins University

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Approach:experimental assay· 1 Organism:human· 1

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Emmanouil TampakakisiD· 1 shared Mackenzie T. PrimroseiD· 1 shared Markus Andreas KelleriD· 1 shared Nanami SenooiD· 1 shared Steven Michael ClaypooliD· 1 shared Yvonne WohlfarteriD· 1 shared

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Developmental BiologyiSciencePeer-reviewedFeb 20, 2026

Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes

Nanami Senoo, Macie S. Sheridan, Yvonne Wohlfarter…·Steven Michael Claypool

This study shows that TAFAZZIN deficiency disrupts mitochondrial maturation in cardiomyocytes, leading to structural and functional impairments associated with Barth syndrome cardiomyopathy.

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