Author

Madeleine K. Lorenger

University of Maine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Dylan J. Wagner· 2 shared Julie A. GosseiD· 2 shared Bailey E. WestiD· 1 shared Bright Obeng· 1 shared Collin T. Frangos· 1 shared Dorothy R. Smith· 1 shared Emily L. LedueiD· 1 shared Emma R. Morrison· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Dylan J. Wagner

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2 papers

Recent·Most cited

Antimicrobial cetylpyridinium chloride disrupts the mitochondrial electron transport chain as potently as cyanide, via cardiolipin interference at cytochrome C

Emily L. Ledue, Noah E. Adelman, Madeleine K. Lorenger, Dylan J. Wagner, Sophie K. Trafton, Esther Biro, Emma R. Morrison, Quinn W. D'Alessio, John E. Burnell, Julie A. Gosse

bioRxiv · Aug 22, 2026 · PreprintPharmacology & Toxicology

Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase

Bright Obeng, Lucas J. Bennett, Bailey E. West, Dylan J. Wagner, Patrick J. Fleming, Morgan N. Tasker, Madeleine K. Lorenger, Dorothy R. Smith, Tetiana Systuk, Sydni M. Plummer, Jeongwon Eom, Marissa D. Paine, Collin T. Frangos, Michael P. Wilczek, Juyoung K. Shim, , Julie A. Gosse

This study shows that cetylpyridinium chloride inhibits mast cell function by disrupting tyrosine phosphorylation of Syk kinase and LAT, without affecting Lyn kinase.

Journal of Immunotoxicology · Dec 31, 2024Peer-reviewedPharmacology & Toxicology