Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content
Cortnie L. Hartwig, Gretchen Macías Méndez, Shatabdi Bhattacharjee, Alysia D. Vrailas‐Mortimer, Stephanie A. Zlatic, Amanda A. H. Freeman, Avanti Gokhale, Mafalda Concilli, Erica Werner, Christie Sapp Savas, Samantha Rudin-Rush, Laura Palmer, Nicole Shearing, Lindsey Margewich, Jacob McArthy, , Victor Faúndez
This study shows that Golgi-dependent copper homeostasis, mediated by ATP7 and COG, is essential for maintaining mitochondrial function and synaptic integrity in neurons.
Journal of Neuroscience · Nov 18, 2020Peer-reviewedNeuroscience