Systemic infections alter cortical transcriptional signatures in Alzheimer's disease
Giulia Pegoraro, Lachlan Ford MacBean, Adam R. Smith, Darren M. Soanes, Rebecca G. Smith, Jennifer L. Imm, Joshua Harvey, Morteza P Kouhsar, Valentin Laroche, Luke Stephen Weymouth, Isabel Castanho, Winston Hide, Laura Palmer, Debra J. Lett, Andrew Robinson, , Katie Lunnon
This study examines how systemic respiratory infections alter transcriptional patterns in the Alzheimer's disease brain, identifying gene expression changes and pathways linked to immune and vascular responses.
Neurobiology of Aging · Jun 26, 2026Peer-reviewedNeuroscience