Large scale functional screen identifies genetic variants with splicing effects in modern and archaic humans
Stephen Rong, Christopher R. Neil, Anastasia Welch, Chaorui Duan, Samantha Maguire, Ijeoma C. Meremikwu, Malcolm Meyerson, Ben J. Evans, William Guy Fairbrother
The paper identifies splicing variants in modern and archaic humans using functional assays and shows differences in purifying selection and adaptive introgression.
Proceedings of the National Academy of Sciences · May 16, 2023Peer-reviewedGenomics