Amino Acid Stress Induces Non-AUG Initiation of c-myc Translation
Miao Zhang, Changqian Zhou, João A. Paulo, Steven P. Gygi, Tracy Keller, Malcolm Whitman
The paper shows that amino acid stress shifts c-myc translation from AUG-initiated to CUG-initiated isoforms via ribosome stalling and queue formation.
bioRxiv · Jul 8, 2026 · PreprintCell Biology