The cationic amino acid exporter Slc7a7 is vital for and induced in tissue macrophages with sustained efferocytic activity
Doris Lou Demy, Mireille Carrère, Ramil R. Noche, Muriel Tauzin, Marion Le Bris, Chooyoung Baek, Malika Yousfi, Ignaty Leshchiner, Wolfram Goessling, Philippe Herbomel
This study shows that Slc7a7 is essential for tissue macrophages with sustained efferocytic activity, as its expression is induced during efferocytosis and supports their survival.
Journal of Cell Science · Sep 24, 2020Peer-reviewedDevelopmental Biology