The role of a G-quadruplex structure in mediating the interactions of miR-1249-3p with the 3-UTR of the HNRNPK mRNA
Manju Kasaju, Rosalia M. Palumbo, Carlan Gray, Lydia Grimaldi, Jacob Shoulders, David B. Heisler, Mihaela‐Rita Mihailescu
This study identifies a G-quadruplex structure in the HNRNPK 3-UTR that modulates miR-1249-3p binding, affecting hnRNP K expression and suggesting a new therapeutic target.
bioRxiv · Oct 12, 2026 · PreprintBiochemistry