David B. Heisler

This study identifies a G-quadruplex structure in the HNRNPK 3-UTR that modulates miR-1249-3p binding, affecting hnRNP K expression and suggesting a new therapeutic target.

The paper identifies G-quadruplex and i-motif structures in SHMT1 5UTR that regulate gene expression, suggesting potential therapeutic targets for multiple sclerosis.

The paper shows that actin-specific toxins from different bacteria inhibit each other's ability to disrupt the host actin cytoskeleton, revealing a mechanism of bacterial competition.