Reversal of carbapenem resistance in Pseudomonas aeruginosa by camelid single domain antibody fragment (VHH) against the C4 dicarboxylate transporter
Anil Kumar Nagraj, Manjiri Shukla, Mansi Kulkarni, Pratik Rajendra Patil, Mrunal Borgave, Sanjiban K. Banerjee
This paper develops a camelid VHH antibody that reverses carbapenem resistance in Pseudomonas aeruginosa by targeting the C4 dicarboxylate transporter, enhancing drug efficacy in a mouse model.
bioRxiv · Jun 20, 2023 · PreprintMolecular Biology