Author

Pratik Rajendra Patil

Heidelberg UniversityORCID 0000-0002-8913-9134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Manjiri Shukla· 2 shared Sanjiban K. BanerjeeiD· 2 shared Agasthya SureshiD· 1 shared Alexander Maxwell BurroughsiD· 1 shared Anil Kumar Nagraj· 1 shared Carlos Costas‐InsuaiD· 1 shared Claudio A.P. JoazeiroiD· 1 shared Federico CerulloiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Manjiri Shukla

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A rapid non-traditional approach for developing biologicals against drug- resistant bacteria and yeasts.

Sanjiban K. Banerjee, Pratik Rajendra Patil, Agasthya Suresh, Rija Nada, Gayatri Naik, Manjiri Shukla

The paper presents a rapid method to develop anti-infective biologicals effective against drug-resistant bacteria and yeasts using antibody-drug conjugates with dual modes of action.

bioRxiv · Mar 15, 2025 · PreprintMicrobiology

Mechanism and evolutionary origins of Alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10

Pratik Rajendra Patil, Alexander Maxwell Burroughs, Mohit Misra, Federico Cerullo, Carlos Costas‐Insua, Hao‐Chih Hung, Ivan Đikić, Lakshminarayanan Aravind, Claudio A.P. Joazeiro

The paper investigates how Pirh2 and CRL2-KLHDC10 E3 ligases recognize Ala-tails, showing conserved binding sites and convergent evolution of their recognition mechanisms.

Cell Reports · Sep 1, 2023Peer-reviewedMolecular Biology

Reversal of carbapenem resistance in Pseudomonas aeruginosa by camelid single domain antibody fragment (VHH) against the C4 dicarboxylate transporter

Anil Kumar Nagraj, Manjiri Shukla, Mansi Kulkarni, Pratik Rajendra Patil, Mrunal Borgave, Sanjiban K. Banerjee

This paper develops a camelid VHH antibody that reverses carbapenem resistance in Pseudomonas aeruginosa by targeting the C4 dicarboxylate transporter, enhancing drug efficacy in a mouse model.

bioRxiv · Jun 20, 2023 · PreprintMolecular Biology