Author

Margaret Heffernan

University of Notre Dame

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angela Mae RichardsoniD· 1 shared Dylan ZhouiD· 1 shared Elise O’HerroniD· 1 shared Jacob KurlanderiD· 1 shared Natasha HockadeniD· 1 shared Nicholas F. DowningiD· 1 shared Scott H. CooperiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Angela Mae RichardsonORCID

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1 paper

Recent·Most cited

Physioxia Reprograms Glioblastoma Cells Enhancing Migration and Altering Therapeutic Sensitivity

Natasha Hockaden, Elise O’Herron, Dylan Zhou, Nicholas F. Downing, Jacob Kurlander, Margaret Heffernan, Scott H. Cooper, Angela Mae Richardson

This study shows that culturing glioblastoma cells under physiological oxygen levels (5% O2) increases migration, alters cell cycle progression, enhances Slug expression, and changes therapeutic sensitivity to 5-fluorouracil.

Cancers · Aug 14, 2026Peer-reviewedCancer Biology