Author

Nicholas F. Downing

Indiana University IndianapolisORCID 0000-0002-8224-5508Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angela Mae RichardsoniD· 1 shared Dylan ZhouiD· 1 shared Elise O’HerroniD· 1 shared Jacob KurlanderiD· 1 shared Margaret Heffernan· 1 shared Natasha HockadeniD· 1 shared Scott H. CooperiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Angela Mae RichardsonORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Cancer BiologyCancersPeer-reviewedAug 14, 2026

Physioxia Reprograms Glioblastoma Cells Enhancing Migration and Altering Therapeutic Sensitivity

Natasha Hockaden, Elise O’Herron, Dylan Zhou…·Angela Mae Richardson

This study shows that culturing glioblastoma cells under physiological oxygen levels (5% O2) increases migration, alters cell cycle progression, enhances Slug expression, and changes therapeutic sensitivity to 5-fluorouracil.

DOI 10.3390/cancers18162620

humanbulk RNA-seq

𝕏 PostBluesky