Genotypic context modulates fitness landscapes: Effects onthe speed and direction of evolution for antimicrobialresistance
C. Brandon Ogbunugafor, Rafael F. Guerrero, Margaret J. Eppstein
This study shows that genotypic context affects the speed and direction of evolution in antimicrobial resistance by altering fitness landscape topography through simulations and engineered bacterial strains.
bioRxiv · Sep 25, 2018 · PreprintEvolutionary Biology