Mapping the druggable targets displayed by human colonic enteroendocrine cells
Yuxian Lei, Bettina Bohl, Leah Meyer, Margot Jacobs, Naila Haq, Xiaoping Yang, Bu Hayee, Kevin G. Murphy, Parastoo Hashemi, Gavin A. Bewick
The paper identifies and catalogs druggable targets in human colonic enteroendocrine cells using bulk and single-cell RNA sequencing, and functionally validates two novel receptors.
bioRxiv · Oct 29, 2024 · PreprintCell Biology