Yuxian Lei

This study shows that activating the Y4R receptor protects β-cells and modulates islet immunity, delaying autoimmune diabetes in multiple models.

This study measures real-time serotonin dynamics in human-derived gut organoids using fast-scan cyclic voltammetry, showing increased release events after forskolin and IBMX stimulation.

The paper identifies and catalogs druggable targets in human colonic enteroendocrine cells using bulk and single-cell RNA sequencing, and functionally validates two novel receptors.