Cell BiologyScience AdvancesPeer-reviewed
Lysosomal uptake of mtDNA mitigates heteroplasmy
Parisa Kakanj, Mari Bonse, Arya Kshirsagar…·David Pla‐Martín
The paper shows that lysosomal uptake of mtDNA reduces heteroplasmy by enhancing mtDNA turnover through retromer-mediated mechanisms in Drosophila.
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