Human cerebral assembloids as a model to study the interaction of glioblastoma with resident glial cells
Sofia Kalpazidou, Polyxeni Moysidou-Tsiorva, Buse Özbaykent, Ecem Balcioglu, Maria Richter, Elijah Shelton, Michael Frischmann, Jovana Spalevic, Patrick N. Harter, Claire Delbridge, Arthur Wagner, Maria Goldberg, Chiara Negwer, Bernhard Meyer, J. Schlegel, , Jovica Ninkovic
This study develops human cerebral assembloids to model glioblastoma interactions with glial cells, revealing extracellular vesicles' role in peritumoral niche formation.
bioRxiv · Oct 1, 2026 · PreprintNeuroscience