Genetic ablation of Sarm1 attenuates axonal degeneration in a mouse model of CMT2J
Anke Claessens, Roberta De Blasis, Cinzia Ferri, Serena Valenzano, Ubaldo Del Carro, Alessandra Mandelli, Roberto Furlan, Yo Sasaki, Maria Laura Feltri, Lawrence G. Wrabetz, Ghjuvan’Ghjacumu Shackleford, Maurizio D’Antonio
This study shows that deleting Sarm1 reduces axonal degeneration in a CMT2J mouse model, but does not fully prevent disease progression.
bioRxiv · Oct 29, 2026 · PreprintNeuroscience