NeurosciencebioRxivPreprint
A partial reduction of Drp1 enhances mitophagy, autophagy, mitochondrial biogenesis, dendritic spines and synaptic activity in a transgenic Tau mouse model of Alzheimer disease
Ramesh J. L. Kandimalla, Maria Mańczak, Jangampalli Adi Pradeepkiran, P. Hemachandra Reddy
This study shows that reducing Drp1 in Tau mice improves cognitive function and mitochondrial health by enhancing autophagy, mitophagy, and synaptic activity.
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