IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial Epithelium
Patricia C. dela Cruz, Basilin Benson, Naresh Doni Jayavelu, Weston T. Powell, Lucille M. Rich, Elizabeth R. Vanderwall, Camille Gates, Maria P. White, Nyssa Becker Samanas, Kourtnie Whitfield, Teal S. Hallstrand, Steven F. Ziegler, Gail H. Deutsch, Matthew C. Altman, Jason S. Debley
This study shows IL-13 suppresses antiviral defenses and enhances proinflammatory pathways in RV-infected bronchial epithelium, contributing to asthma exacerbations.
bioRxiv · Dec 8, 2025 · PreprintCell Biology