Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network
Soumitra Polley, Tobias Raisch, Marie Koerner, Melina Terbeck, Frauke Gräter, Stefan Raunser, Camilo A. Aponte-Santamaria, Ingrid R. Vetter, Andrea Musacchio
The paper presents a structural and functional analysis of the KMN network, revealing key interfaces and their role in stabilizing microtubule binding and force transmission during chromosome segregation.
bioRxiv · Aug 7, 2023 · PreprintMolecular Biology