Ingrid R. Vetter

The paper identifies a high-affinity master docking motif on CENP-U that interacts extensively with PLK1's Polo-box domain, suggesting common features among master PLK1 docking motifs.

The paper identifies M18BP1 dimerization and its interaction determinants as key for centromere specification through epigenetic mechanisms in humans.

This study identifies Bora as essential for Aurora A-mediated phosphorylation of PLK1's Thr210, revealing a unique interaction required for this process.

The paper identifies a novel RhoA binding site in the ROCK1 PHC1 domain that mediates Rho activity transduction to Myosin II activation.

The paper identifies a phosphorylation network regulated by PLK1 that controls a conformational switch necessary for CENP-A deposition, essential for centromere maintenance.

This study characterizes the auto-inhibited state of Mical1 and shows how Rab8 binding releases inhibition through structural and biochemical analysis.

The paper presents a structural and functional analysis of the KMN network, revealing key interfaces and their role in stabilizing microtubule binding and force transmission during chromosome segregation.

The paper reports the cryo-EM and crystal structures of XaxAB pore complex and monomers, revealing the mechanism of membrane insertion and function of Xax toxins.