Time-limited alterations in cortical activity of a Knock-in mice model of KCNQ2-related Developmental and Epileptic Encephalopathy
Najoua Biba, Hélène Becq, Emilie Pallesi‐Pocachard, Stefania Sarno, Samuel Granjeaud, Aurélie Montheil, Marie Kurz, Laurent Villard, Mathieu Milh, Pierre‐Pascal Lenck‐Santini, Laurent Aniksztejn
This study investigates the developmental changes in neuronal activity in a KCNQ2 knock-in mouse model, finding time-limited alterations in excitability and M-current density that resolve with maturation.
The Journal of Physiology · Apr 7, 2022Peer-reviewedNeuroscience