Laurent Villard

The paper systematically analyzes chrX genes to predict disease associations, identifying 235 genes likely involved in disorders and reporting damaging variants in CDK16 and TRPC5 in patients with intellectual disability or autism.

This study investigates the developmental changes in neuronal activity in a KCNQ2 knock-in mouse model, finding time-limited alterations in excitability and M-current density that resolve with maturation.

The paper identifies a persistent potassium current (IM) that interacts with the persistent sodium current (INaP) to regulate locomotion speed in neonatal rodents.

This study shows that increasing HTT phosphorylation at Ser421 improves BDNF transport, striatal BDNF availability, and the phenotype of Mecp2 knockout mice.