Low base-substitution mutation rate in the germline genome of ciliate Tetrahymena thermophila
Hongan Long, David J Winter, Allan Y-C Chang, Way Sun, Steven H. Whu, Mariel Balboa, Ricardo BR Azevedo, Reed A Cartwright, Michael Lynch, Rebecca A Zufall
The paper measures the germline base-substitution mutation rate in Tetrahymena thermophila and finds it to be low, similar to Paramecium tetraurelia, but notes fitness decline in exclusion lines suggests other factors contribute to mutational load.
Genome Biology and Evolution · Sep 15, 2016Peer-reviewedEvolutionary Biology