Suppressor mutations in Mecp2-null mice reveal that the DNA damage response is key to Rett syndrome pathology
Adebola Enikanolaiye, Julie Ruston, Rong Zeng, Christine Taylor, Marijke Schrock, Christie M. Buchovecky, Jay Shendure, Elif Fidan Acar, Monica J. Justice
The paper identifies suppressor mutations in Mecp2-null mice that alleviate Rett syndrome symptoms by modulating DNA damage response pathways.
Genome Research · Apr 1, 2020Peer-reviewedGenetics