Visible traits demonstrate that crispant founder mice can be used for phenotypic assessment
Rebekah Tillotson, Marina Gertsenstein, Li‐Hsin Chang, Julie Ruston, Fernando Bellido Molías, Lauri G. Lintott, Christine Taylor, Philippe Emmanuel Gautier, Lauryl M. J. Nutter, Monica J. Justice
This study shows that crispant founder mice can be used for phenotypic assessment despite genetic mosaicism, as observed null phenotypes were present in up to 100% of founders.
bioRxiv · Jun 27, 2025 · PreprintGenetics