In vivo imaging of reactive oxygen species after myocardial ischemia-reperfusion injury: a large animal multimodal imaging and transcriptomic study
Sophia Swago, Chiara Camillo, Marina Awad, Evan P. Gallagher, Elizabeth W. Thompson, Estíbaliz Castillero, Ting Peng, Liming Pei, Zhiliang Cheng, Andrew Tsourkas, Robert C. Gorman, Victor A. Ferrari, Meagan J. McManus, Robert H. Mach, Joel S. Karp, , Paco Eduardo Bravo
This study uses multimodal imaging and transcriptomics to show increased reactive oxygen species activity in myocardial tissue and systemic organs after myocardial infarction, with associated gene expression changes.
bioRxiv · Dec 8, 2025 · PreprintBioengineering