Author

Mario Garcia

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:protein structure· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chengsheng MaoiD· 1 shared Feixiong ChengiD· 1 shared Gabriel J. RockliniD· 1 shared Maalavika PillaiiD· 1 shared Meghan R. HutchiD· 1 shared Mia S. BroadiD· 1 shared Sanaz Ghotbaldini· 1 shared Saya DennisiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Chengsheng MaoORCID

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2 papers

Recent·Most cited

Evaluating zero-shot prediction of protein design success by AlphaFold, ESMFold, and ProteinMPNN

Mario Garcia, Sugyan M. Dixit, Gabriel J. Rocklin

This study evaluates how well AlphaFold2, ESMFold, and ProteinMPNN predict the success of de novo protein designs using confidence metrics, finding that ESMFold performs best but overall accuracy is limited.

bioRxiv · Jul 29, 2025 · PreprintBioinformatics

SOAR elucidates disease mechanisms and empowers drug discovery through spatial transcriptomics

Yiming Li, Saya Dennis, Meghan R. Hutch, Yanyi Ding, Yadi Zhou, Yawei Li, Maalavika Pillai, Sanaz Ghotbaldini, Mario Garcia, Mia S. Broad, Chengsheng Mao, Feixiong Cheng, Zexian Zeng, Yuan Luo

SOAR provides a curated spatial transcriptomics database and analysis tools to facilitate disease mechanism studies and drug discovery.

bioRxiv · Apr 17, 2022 · PreprintBioinformatics