Saya Dennis

This study compares DNA methylation profiles of breast tumors, adjacent normal tissues, and healthy controls to identify epigenetic differences and their association with estrogen receptor status.

The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.

SOAR provides a curated spatial transcriptomics database and analysis tools to facilitate disease mechanism studies and drug discovery.

This study uses machine learning to predict Parkinson's disease onset and subtype from germline variants, achieving ROC scores of 0.77 and 0.61.