Sugyan M. Dixit

Integrative Network Analysis Reveals Organizational Principles of the Endocannabinoid System

The paper presents a systems-level analysis of the endocannabinoid system (ECS) using network integration, identifying hubs, communities, and resilience mechanisms.

Large-scale discovery, analysis, and design of protein energy landscapes

The paper measures conformational fluctuations of protein domains using hydrogen-deuterium exchange mass spectrometry and uses computational modeling to design mutations that stabilize low-stability segments.

Evaluating zero-shot prediction of protein design success by AlphaFold, ESMFold, and ProteinMPNN

This study evaluates how well AlphaFold2, ESMFold, and ProteinMPNN predict the success of de novo protein designs using confidence metrics, finding that ESMFold performs best but overall accuracy is limited.