Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor
E. Johanna L. Stéen, Efthalia-Natalia Tousiaki, Lee P. Kingston, Berend van der Wildt, Nikolett Lénárt, Wissam Beaino, Mariska Verlaan, Barbara A. Zarzycka, Bastian Zinnhardt, Ádám Dénes, Luca B. Gobbi, Iwan J. P. de Esch, Charles S. Elmore, Albert D. Windhorst, Michael Honer, Rob Leurs
This paper characterizes [3H]AZ12464237 as a high-affinity radioligand for the P2Y12 receptor, showing selectivity and utility in in vitro studies.
Biochemical Pharmacology · Apr 3, 2025Peer-reviewedPharmacology & Toxicology