Author

Barbara A. Zarzycka

Vrije Universiteit AmsterdamORCID 0000-0002-7202-5317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Iwan J. P. de EschiD· 2 shared Rob LeursiD· 2 shared Ádám DénesiD· 1 shared Albert D. WindhorstiD· 1 shared Andy ChevignéiD· 1 shared Bastian ZinnhardtiD· 1 shared Berend van der WildtiD· 1 shared Charles S. ElmoreiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

Iwan J. P. de EschORCID

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2 papers

Recent·Most cited

Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor

E. Johanna L. Stéen, Efthalia-Natalia Tousiaki, Lee P. Kingston, Berend van der Wildt, Nikolett Lénárt, Wissam Beaino, Mariska Verlaan, Barbara A. Zarzycka, Bastian Zinnhardt, Ádám Dénes, Luca B. Gobbi, Iwan J. P. de Esch, Charles S. Elmore, Albert D. Windhorst, Michael Honer, Rob Leurs

This paper characterizes [3H]AZ12464237 as a high-affinity radioligand for the P2Y12 receptor, showing selectivity and utility in in vitro studies.

Biochemical Pharmacology · Apr 3, 2025Peer-reviewedPharmacology & Toxicology

Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3

Sophie Bérenger, Justyna M. Adamska, Francesca Deflorian, Chris de Graaf, Christie B. Palmer, Martyna Szpakowska, Andy Chevigné, Iwan J. P. de Esch, Barbara A. Zarzycka, Henry F. Vischer, Maikel Wijtmans, Rob Leurs

This paper designs and characterizes the first photoswitchable small-molecule agonist for ACKR3, showing its selectivity and light-controlled activation properties.

ACS Omega · Feb 18, 2025Peer-reviewedPharmacology & Toxicology