ASD gene Bcl11a regulates subcellular RNA localization, associative circuitry, and social behavior
Omer Durak, Ji‐Yoon Kim, Dustin E. Tillman, Yasuhiro Itoh, Marit R. Wettstein, Luciano Custo Greig, Thomas A. Addison, Jeffrey D. Macklis
This study shows that the ASD/ID gene Bcl11a is essential for precise axonal targeting and circuit formation in CPN, with its deletion causing behavioral and molecular disruptions in mice.
bioRxiv · Oct 6, 2022 · PreprintNeuroscience