Effect of Stroma-directed Drugs in Combination with Chemotherapy Against Pancreatic Cancer- a Preclinical Study
Mamta Gupta, Hoon Choi, Emma Elizabeth Furth, Sydney M. Shaffer, Stephen Pickup, Cynthia J. Clendenin, Fang Liu, Quy Cao, Hee Kwon Song, Yong Fan A, Jeffrey Duda, James C. Gee, Thomas Benjamin Karasic, Mark Alan Rosen, Peter O’Dwyer, Rong Zhou
This study compares chemotherapy with and without stroma-directed drugs in a mouse model of pancreatic cancer, finding enhanced tumor growth inhibition and changes in tumor microenvironment.
bioRxiv · Dec 24, 2024 · PreprintCancer Biology