Author

Mark Bruce

Oxford Nanopore Technologies (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandar P. IvanoviD· 1 shared Andrew J Heron· 1 shared Anthony Warland· 1 shared Botond Sipos· 1 shared Caroline KochiD· 1 shared Chris Wright· 1 shared Daniel J Turner· 1 shared Daniel Jachimowicz· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

Aleksandar P. IvanovORCID

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2 papers

Recent·Most cited

Machine Learning-Driven Nanopore Sensing for Quantitative, Label-Free miRNA Detection

Caroline Koch, Seshagiri Sakthimani, Victoria Maria Noakes, Miruna T. Cretu, David Newman, Richard Gutierrez, Mark Bruce, Julia Gorelik, Nadia Guerra, Joshua B. Edel, Aleksandar P. Ivanov

This paper develops a nanopore-based assay with machine learning for label-free miRNA detection, showing that a CNN outperforms traditional methods in sensitivity and classification.

Small Methods · Jan 19, 2026Peer-reviewedBiophysics

Highly parallel direct RNA sequencing on an array of nanopores

Daniel R Garalde, Elizabeth A Snell, Daniel Jachimowicz, Andrew J Heron, Mark Bruce, Joseph Lloyd, Anthony Warland, Nadia Pantic, Tigist Admassu, Jonah Ciccone, Sabrina Serra, Jemma Keenan, Samuel Martin, Luke McNeill, Jayne Wallace, , Daniel J Turner

This paper demonstrates direct RNA sequencing using an array of nanopores, offering advantages over traditional RNA-seq methods by avoiding amplification and reverse transcription biases.

bioRxiv · Aug 12, 2016Genomics