Author

Mark R. Fielden

Amgen (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Charles C. ValentineiD· 1 shared Jesse J. SalkiD· 1 shared Lindsey N. WilliamsiD· 1 shared Robert R. YoungiD· 1 shared Rohan M. KulkarniiD· 1 shared Sheroy MinocherhomjiiD· 1 shared Tan LiiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Charles C. ValentineORCID

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1 paper

Recent·Most cited

Direct Quantification of in vivo Mutagenesis and Carcinogenesis Using Duplex Sequencing

Charles C. Valentine, Robert R. Young, Mark R. Fielden, Rohan M. Kulkarni, Lindsey N. Williams, Tan Li, Sheroy Minocherhomji, Jesse J. Salk

This paper demonstrates that Duplex Sequencing, an error-corrected NGS method, can accurately quantify in vivo mutagenesis and early signs of carcinogenesis in mice, outperforming traditional transgenic rodent assays.

Proceedings of the National Academy of Sciences · Dec 14, 2020Peer-reviewedGenomics