Lindsey N. Williams

This paper evaluates a DuplexSeq-based mutagenesis assay in ENU-exposed rats, showing early detection of mutations and reproducible results across tissues and labs.

The paper examines how mitochondrial haplotype and mito-nuclear matching influence somatic mutation and selection in aging mice across tissues.

This paper demonstrates that Duplex Sequencing, an error-corrected NGS method, can accurately quantify in vivo mutagenesis and early signs of carcinogenesis in mice, outperforming traditional transgenic rodent assays.