Mark Yandell

Accelerated selection of a viral RNA polymerase variant during gene copy number amplification promotes rapid evolution of vaccinia virus

This study shows how vaccinia virus adapts to host immune defenses through point mutations in RNA polymerase and gene copy number variation, accelerating the spread of beneficial mutations.

Antimicrobial functions of lactoferrin promote genetic conflicts in ancient primates and modern humans

This study investigates the evolutionary role of lactoferrin's antimicrobial functions in primate and human genetic conflicts, showing evidence of positive selection and links to modern genetic variation.