Author

Marle Pretorius

University of Calgary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Carol HuangiD· 1 shared Qianyu Xie· 1 shared Raneet Kahlon· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperPhysiology

Carol HuangORCID

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1 paper

Recent·Most cited

Lrrc55 modulates beta-cell resilience and calcium transporter expression under metabolic and physiologic stress

Marle Pretorius, Raneet Kahlon, Qianyu Xie, Carol Huang

This study shows Lrrc55 protects beta-cells from glucolipotoxicity by modulating ER calcium handling and reducing apoptosis, but may negatively regulate insulin secretion.

bioRxiv · Nov 3, 2025 · PreprintPhysiology