Carbonic anhydrase 4 disruption and pharmacological inhibition reduce synaptic and behavioral adaptations following oxycodone withdrawal
Subhash Chandra Gupta, Rebecca J. Taugher, Ali Ghobbeh, Marshal T. Jahnke, Rong Fan, Ryan T. LaLumiere, John A. Wemmie
This study shows that disrupting or inhibiting carbonic anhydrase 4 reduces synaptic and behavioral adaptations during oxycodone withdrawal in mice.
bioRxiv · Jan 23, 2025 · PreprintNeuroscience