Author

Martha E. Lopez‐Burks

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anne L. CalofiD· 2 shared Arthur D. LanderiD· 2 shared Stephenson CheaiD· 2 shared Adam L. MacLeaniD· 1 shared Jesse KregeriD· 1 shared Rosaysela SantosiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersDevelopmental Biology

Anne L. CalofORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMay 15, 2025

Interaction between long-range chromatin regulators Nipbl & Isl1 synergistically drives heart defects in mice

Stephenson Chea, Rosaysela Santos, Martha E. Lopez‐Burks…·Anne L. Calof

This study shows that combined haploinsufficiency of Nipbl and Isl1 in mice leads to more severe congenital heart defects than either gene deficiency alone.

1 citation

mousebulk RNA-seq

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Developmental BiologyScience AdvancesPeer-reviewedMar 20, 2024

Gastrulation-stage gene expression in Nipbl+/- mouse embryos foreshadows the development of syndromic birth defects

Stephenson Chea, Jesse Kreger, Martha E. Lopez‐Burks…·Anne L. Calof

The paper identifies gene expression changes in Nipbl+/- mouse embryos during gastrulation that link Nipbl-deficiency to birth defects via mesoderm lineage misallocation and Nanog overexpression.

11 citations

mousescRNA-seq

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