Author

Rosaysela Santos

Kaiser Permanente Bernard J. Tyson School of MedicineORCID 0009-0007-0614-5031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anne L. CalofiD· 3 shared Arthur D. LanderiD· 3 shared Ebony FlowersiD· 2 shared Kyoko YokomoriiD· 2 shared Richard Chien· 2 shared Shimako KawauchiiD· 2 shared Yen-Yun Chen· 2 shared Alexander R. Ball· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Anne L. CalofORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMay 15, 2025

Interaction between long-range chromatin regulators Nipbl & Isl1 synergistically drives heart defects in mice

Stephenson Chea, Rosaysela Santos, Martha E. Lopez‐Burks…·Anne L. Calof

This study shows that combined haploinsufficiency of Nipbl and Isl1 in mice leads to more severe congenital heart defects than either gene deficiency alone.

1 citation

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintJun 4, 2019

The cohesin loader NIPBL interacts with pre-ribosomal RNA and treacle to regulate ribosomal RNA synthesis

Xiangduo Kong, Yen-Yun Chen, Jianhuang Lin…·Kyoko Yokomori

This study identifies NIPBL's interaction with RNA and treacle in regulating pre-rRNA transcription and nucleolar organization.

3 citations

humanexperimental assay

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Developmental BiologyClinical EpigeneticsPeer-reviewedAug 25, 2017

The Effect Of Nipped-B-Like (Nipbl) Haploinsufficiency On Genome-Wide Cohesin Binding And Target Gene Expression: Modeling Cornelia de Lange Syndrome

Daniel A. Newkirk, Yen-Yun Chen, Richard Chien…·Kyoko Yokomori

This study examines how Nipbl haploinsufficiency affects cohesin binding and gene expression in mice, linking reduced cohesin function to CdLS-related gene dysregulation.

44 citations

mouseChIP-seq

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