Tracking changes in functionality and morphology of repopulated microglia in young and old mice
Zuzanna M. Luczak-Sobotkowska, Patrycja Rosa, María Banqueri, Natalia Ochocka, Anna Kiryk, Anna M. Lenkiewicz, Martin Furhmann, Aleksander Jankowski, Bozena Kaminska
The paper studies repopulated microglia in young and old mice using scRNA-seq and other methods, finding they originate from progenitors, reconstitute functional clusters, and show increased inflammation and distinct morphology in aging.
Journal of Neuroinflammation · Oct 3, 2024Peer-reviewedNeuroscience