Author

Masahito Irie

Tokyo Medical and Dental University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Fumitoshi IshinoiD· 2 shared Tomoko Kaneko‐IshinoiD· 2 shared Ayumi Matsuzawa· 1 shared Hirosuke ShiuraiD· 1 shared Johbu ItohiD· 1 shared Masanobu YoshikawaiD· 1 shared Takashi KohdaiD· 1 shared Toru SuzukiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersMolecular Biology

Fumitoshi IshinoORCID

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2 papers

Recent·Most cited

A eutherian-specific metaviral gene, RTL6, coordinates microglial inflammatory responsiveness and state regulation

Fumitoshi Ishino, Masahito Irie, Hirosuke Shiura, Takashi Kohda, Tomoko Kaneko‐Ishino

This study identifies RTL6 as a eutherian-specific gene that regulates microglial inflammatory responses and functional state transitions through its role in LPS signaling.

bioRxiv · Jul 16, 2026 · PreprintMolecular Biology

RTL4, a retrovirus-derived gene implicated in autism spectrum disorder, is a microglial gene that responds to noradrenaline in the postnatal brain

Fumitoshi Ishino, Johbu Itoh, Ayumi Matsuzawa, Masahito Irie, Toru Suzuki, Yuichi Hiraoka, Masanobu Yoshikawa, Tomoko Kaneko‐Ishino

This study identifies RTL4 as a microglial gene responsive to noradrenaline, showing its expression dynamics and role in brain adaptation and neuronal network development.

International Journal of Molecular Sciences · Dec 23, 2024Peer-reviewedMolecular Biology